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March 3, 2026JAMA Surgery3 citations

Fluorescence-Guided Surgery—Illuminating the Limits of Cancer Therapeutics

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HTHidenori TanakaSGShravan GowrishankarEREben L. Rosenthal

Key Points

  • Fluorescence-guided surgery enhances drug delivery understanding in cancer therapy, potentially boosting treatment efficacy.
  • This method utilizes optically labeled therapeutic antibodies to illuminate tumor margins during surgery.
  • Observational analysis of drug delivery mechanisms highlights challenges in current cancer therapies and their limitations.
  • This viewpoint emphasizes the need for further exploration of optical techniques to optimize therapeutic outcomes in oncology.

Abstract

This Viewpoint describes the use of optically labeled therapeutic antibodies in fluorescence-guided surgery to advance understanding of drug delivery in cancer therapy.

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Cite This Study

Tanaka et al. (2026) studied this question.

synapsesocial.com/papers/69a75d40c6e9836116a26f50https://doi.org/10.1001/jamasurg.2025.6246
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