Why the study?
To assess whether routine postoperative enoximone infusion compared with dobutamine improved clinical and biochemical results after coronary artery bypass grafting with cardiopulmonary bypass.
Does postoperative enoximone infusion reduce cardiac enzyme release and improve clinical outcomes compared to dobutamine in patients undergoing CABG?
Does postoperative enoximone infusion reduce cardiac enzyme release and improve clinical outcomes compared to dobutamine in patients undergoing CABG?
Routine postoperative enoximone infusion after CABG reduces cardiac enzyme release and the need for escalating inotropic support compared to dobutamine, without changing hard clinical outcomes.
Authors
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Should not change postoperative inotrope selection after CABG; leaves open hard outcome benefit pending randomized confirmation.
F et al. (2004) studied this question.
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