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March 3, 2026World Journal of PsychiatryOpen Access

L-shaped association between fasting blood glucose and comorbid anxiety in Chinese patients with first-episode untreated major depressive disorder

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Authors

LYLian YuanJLJunjun LiuZLZhe Li

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Overview

Observational analysis finds an L-shaped relationship between fasting blood glucose and anxiety in Chinese MDD patients, indicating increased risk.

Key Points

  • An elevated risk of comorbid anxiety is linked to lower fasting blood glucose levels.
  • Specifically, when fasting blood glucose falls below 4.8 mmol/L, the anxiety risk increases significantly.
  • Analysis based on first-episode untreated major depressive disorder in Chinese Han individuals reveals notable patterns.
  • These findings highlight a need for attention to glucose levels in managing anxiety within depressive disorders.

Cite This Study

Yuan et al. (2026) studied this question.

synapsesocial.com/papers/69a75d78c6e9836116a278eehttps://doi.org/10.5498/wjp.v16.i2.113063
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