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January 1, 2026Medical Journal Armed Forces India

Ovarian dysgerminoma in a prepubertal female with tumour-confined mosaic monosomy X: A rare case report and cytogenetic insights

Ankita Sharma Varun Bajaj Barun Kumar Chakrabarty S. Venkatesan

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Key Points

Dysgerminoma was observed in a prepubertal female, highlighting the rare occurrence of this tumor type at a young age.
Cytogenetic analysis revealed tumor-confined mosaic monosomy X, which is significant in understanding the genetic background of these tumors.
The identification of mosaic monosomy X may inform future approaches to diagnose and manage similar cases in young patients.
Recognizing such rare cases emphasizes the need for detailed cytogenetic evaluation in pediatric tumors.

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Implication

Case report reveals tumor-confined dysgerminoma with mosaic monosomy X in a prepubertal female, suggesting genetic insights.

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Cite This Study

Sharma et al. (2026) studied this question.

synapsesocial.com/papers/69a75d7ec6e9836116a2798c https://doi.org/10.1016/j.mjafi.2025.12.011

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Dysgerminoma of the OvaryOriginal Research · 2021 · 19 citations
2Ovarian Dysgerminoma: A Tertiary Center ExperienceOriginal Research · 2020 · 21 citations
3KIT gene mutation and amplification in dysgerminoma of the ovaryOriginal Research · 2010 · 99 citations
4Uncommon Metastasis of Ovarian Dysgerminoma: A Case Report and Review of the LiteratureCase Report · 2021 · 17 citations
5Pitfalls of Ovarian DysgerminomaNarrative Review · 2023 · 1 citations

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