Association between histogram parameters of T2 weighted MRI data, WHO grade, tumor proliferation index and selected molecular markers in low-grade glioma

Georg Gihr; Hans Henkes; Ali Khanafer; Mehdi Allouche; Oliver Ganslandt; Sebastian Johannes Müller; Walter A. Wohlgemuth; Stefan Schob

doi:10.3389/fradi.2026.1730316

January 29, 2026Frontiers in RadiologyOpen Access

Association between histogram parameters of T2 weighted MRI data, WHO grade, tumor proliferation index and selected molecular markers in low-grade glioma

View Full Paper

Ask AI

Bookmark

Share

Key Points

T2 SI Entropy effectively distinguishes between grade 1 and grade 2 gliomas, highlighting its diagnostic potential.
The study indicates a correlation between T2 SI Entropy and Ki-67 expression, a marker of tumor proliferation.
Analysis of MRI data showcases how tumor heterogeneity is assessed through histogram parameters.
Findings support the role of T2 SI Entropy in evaluating tumor characteristics, important for treatment planning.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Observational analysis finds T2 SI Entropy predicts glioma grade and proliferative activity in low-grade gliomas, suggesting a valuable diagnostic tool.

Abstract

Our investigation demonstrates the potential of T2 SI Entropy in distinguishing grade 1 from grade 2 gliomas and in reflecting the proliferative activity denoted by Ki-67 expression, therefore being a promising HA feature for assessing tumor heterogeneity.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Gihr et al. (2026) studied this question.

synapsesocial.com/papers/69a75d99c6e9836116a27c78 https://doi.org/10.3389/fradi.2026.1730316

View Full Paper

Ask AI

Bookmark

Share

Association between histogram parameters of T2 weighted MRI data, WHO grade, tumor proliferation index and selected molecular markers in low-grade glioma

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Association between histogram parameters of T2 weighted MRI data, WHO grade, tumor proliferation index and selected molecular markers in low-grade glioma

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading