Secondary hemophagocytic lymphohistiocytosis concurrent with febrile infection-related epilepsy syndrome in a child

Oi-Wa Chan; Chun-Nun Chao; Shao-Hsuan Hsia; En-Pei Lee; Kuang-Lin Lin; Jainn-Jim Lin

doi:10.1016/j.seizure.2026.01.015

January 29, 2026SeizureOpen Access

Secondary hemophagocytic lymphohistiocytosis concurrent with febrile infection-related epilepsy syndrome in a child

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Key Points

Child presented with seizures linked to febrile infection, exhibiting symptoms of secondary hemophagocytic lymphohistiocytosis.
Elevated cytokines indicating significant immune dysregulation were measured, showing a clear connection between the two conditions.
Clinical assessment emphasized the role of neuroinflammation in exacerbating seizure activity during febrile episodes.
Findings highlight the need for careful monitoring and treatment protocols in pediatric cases of concurrent syndromes.

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Implication

Observation finds secondary hemophagocytic lymphohistiocytosis coinciding with febrile infection-related epilepsy syndrome, suggesting complex immune interactions.

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Cite This Study

Chan et al. (2026) studied this question.

synapsesocial.com/papers/69a75d9ec6e9836116a27ccb https://doi.org/10.1016/j.seizure.2026.01.015

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Secondary hemophagocytic lymphohistiocytosis concurrent with febrile infection-related epilepsy syndrome in a child

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Secondary hemophagocytic lymphohistiocytosis concurrent with febrile infection-related epilepsy syndrome in a child

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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