Multidrug resistance transporter EmrE is only moderately sensitive to lipid composition

Key Points

• EmrE shows moderate sensitivity to lipid composition, impacting multidrug resistance.
• Alterations in lipid composition influence transporter function, crucial for cellular drug management.
• Analysis of membrane dynamics was conducted to assess the role of lipid environment in transporter activity.
• This finding suggests possible pathways for overcoming drug resistance in clinical settings.