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March 3, 2026Translational Cancer ResearchOpen Access

Efficacy and safety of neoadjuvant chemotherapy combined with concurrent chemoradiotherapy and concurrent chemoradiotherapy alone in locally advanced cervical cancer: a systematic review and meta-analysis

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Authors

YLYaqiong LuJZJing ZhaoZJZhihong Jia

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Overview

Meta-analysis reveals combined neoadjuvant chemotherapy increases initial effects in locally advanced cervical cancer, indicating potential therapy improvements.

Key Points

  • Combined neoadjuvant chemotherapy shows higher initial effectiveness compared to concurrent chemoradiotherapy alone.
  • The platinum regimen presents as a promising option, but careful monitoring for leucopenia is necessary.
  • Systematic review and meta-analysis assess therapeutic outcomes in locally advanced cervical cancer patients.
  • Further prospective studies with larger sample sizes are essential for optimizing treatment strategies.

Cite This Study

Lu et al. (2026) studied this question.

synapsesocial.com/papers/69a75debc6e9836116a28396https://doi.org/10.21037/tcr-2025-966
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