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Long-term exposure to Di(2-ethylhexyl) phthalate induced uterine histopathologic alterations in female mice | Synapse
March 3, 2026
Long-term exposure to Di(2-ethylhexyl) phthalate induced uterine histopathologic alterations in female mice
JL
Je Yeon Lee
JK
Jin Su Kim
Korea Institute of Radiological and Medical Sciences
JZ
Javeria Zaheer
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Key Points
Uterine histopathological alterations were observed following prolonged exposure to di(2-ethylhexyl) phthalate.
Key changes included significant cellular alterations in specific tissues after exposure duration matching developmental stages.
Observational analysis of female mice exposed to varying concentrations of di(2-ethylhexyl) phthalate revealed notable impacts on uterine health.
Findings suggest potential long-term endocrine disruption, highlighting the need for further investigations into health implications.
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Cite This Study
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Lee et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75e13c6e9836116a28707
https://doi.org/https://doi.org/10.1016/j.taap.2026.117738