SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation response

Key Points

• SOD2 plays a critical role in promoting an adaptive response during cellular starvation.
• The study highlights the interaction between oxidative stress and proteasomal degradation.
• Using various assays, the research reveals how SOD2 modulates cellular pathways responding to nutrient deprivation.
• Significantly, understanding SOD2's function could lead to novel therapeutic strategies for stress-related diseases.