Feasibility study demonstrates diagnostic accuracy in assessing Hirschsprung disease using fluorescence confocal microscopy.
FCM is an easy-to-implement method for identifying normal and affected bowel in HD. It is used on unfixed specimens, preserving the tissue quality. Its diagnostic accuracy is comparable to that of frozen sections in assessable samples, and it is advantageous in cases where local access to expert pathologists is limited.
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Braun et al. (2026) studied this question.
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