Salicylic Acid-Elicited Alkaloid Accumulation in Pinellia ternata Microtubers: Cytotoxicity and Transcriptomic Analysis

Key Points

• Alkaloid accumulation increases in microtubers treated with salicylic acid, enhancing their pharmacological potential.
• Cytotoxicity tests indicate that these alkaloids maintain beneficial effects while limiting harmful impacts on cells.
• Transcriptomic analysis demonstrates changes in gene expression associated with salicylic acid treatment, unveiling molecular pathways.
• These findings indicate potential strategies for improving alkaloid production in Pinellia ternata to meet clinical needs.