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January 1, 2026Annales de Toxicologie Analytique

Pathophysiological and therapeutic insights into Viperidae envenomation: Mechanisms, clinical manifestations, and advances in antivenom strategies

Abderrezak Khelfi

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Key Points

Envenomation leads to significant clinical manifestations, including coagulation disorders and neurotoxicity, which can be life-threatening.
Antivenom strategies reveal a 30% increase in effectiveness compared to older formulations, indicating improved patient outcomes.
Assessment of therapeutic strategies indicates a decrease in fatality rates following updated antivenom applications over the last decade.
The findings support the need for continuous antivenom enhancement and further research in pathophysiological mechanisms for effective treatment.

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Implication

Observational analysis reviews mechanisms and clinical manifestations of Viperidae envenomation, highlighting advances in antivenom strategies.

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Cite This Study

Abderrezak Khelfi (2026) studied this question.

synapsesocial.com/papers/69a75eddc6e9836116a29d68 https://doi.org/10.1016/j.toxac.2026.01.002

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