Using Porcine Gastric Mucin Coated Magnetic Beads to Concentrate and Purify Infectious Human Noroviruses for Infectivity Assays with Human Intestinal Enteroids and Zebrafish

Key Points

• The procedure effectively purifies infectious noroviruses, improving the quality of infectivity assays.
• Key evidence shows a significant enhancement in purity levels using mucin-coated magnetic beads during the assays.
• Assessment using mucin-coated magnetic beads reveals their efficiency in concentrating noroviruses from samples.
• This method may enable more accurate infectivity assessments, potentially leading to improved strategies against norovirus outbreaks.