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January 31, 2026Microchimica Acta

Current status and future challenges of transition-metal oxides as enzyme-mimetics for detection of clinically relevant biomarkers: a comprehensive review

Mani Arivazhagan Paramasivam Shanmugam Lalitha Gnanasekaran Shanmugapriya D Samikannu Prabu S Boonyuen Ayyanu Ravikumar Arunjegan Amalraj Jaroon Jakmunee

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Key Points

Transition-metal oxides can function effectively as enzyme-mimetics, providing potential for improved biomarker detection.
The review emphasizes challenges such as stability in biological environments and selectivity for specific biomolecules.
Critical analysis of current methodologies highlights the need for innovation in enzyme-mimetic applications for diagnostics.
Future research is called for to enhance the efficiency of transition-metal oxides, aiming to improve clinical impact.

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Implication

Comprehensive review reveals current challenges and future directions for transition-metal oxides as enzyme-mimetics in biomarker detection.

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Cite This Study

Arivazhagan et al. (2026) studied this question.

synapsesocial.com/papers/69a75f5cc6e9836116a2aaff https://doi.org/10.1007/s00604-026-07876-0

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