Effects of lysate/tissue storage at −80°C on subsequently extracted EVs of epithelial ovarian cancer tissue origins

Key Points

• Extracellular vesicles yield is influenced by storage conditions, impacting biomarker potential.
• The study finds considerable changes in vesicle properties after long-term storage at -80°C.
• Assessment through comparative analyses demonstrates significant variations across samples.
• Results indicate further investigation is warranted to optimize storage protocols for clinical applications.