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March 3, 2026
Open Access
In vivo lipofuscin quantification by visible-light optical coherence tomography-based fundus autofluorescence imaging
RZ
Rui Zhou
Florida International University
YL
Yiwen Li
University of Miami
RW
Rong Wen
University of Miami
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Key Points
Lipofuscin quantification reveals significant insights into retinal health, indicating possible early disease detection.
Quantification was achieved through visible-light optical coherence tomography-based autofluorescence imaging.
This study employed in vivo imaging techniques to measure lipofuscin accumulation in the fundus of the eye.
Findings suggest the method may enable non-invasive assessments of retinal aging and disease progression.
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In vivo lipofuscin quantification by visible-light optical coherence tomography-based fundus autofluorescence imaging | Synapse
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Zhou et al. (Wed,) studied this question.
synapsesocial.com/papers/69a76036c6e9836116a2cb9c
https://doi.org/https://doi.org/10.1016/j.isci.2026.114903