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March 3, 2026SHILAP Revista de lepidopterología0 citationsOpen Access

Single-cell transcriptomics identifies fibroblast associated immune heterogeneity and prognostic signatures in bladder cancer

XTXiaojuan TangLLLing LiuMGMin Gao

Key Points

  • Bladder cancer shows distinct immune heterogeneity linked with fibroblast activity, indicating diverse patient responses.
  • The findings highlight specific prognostic signatures that may serve as valuable biomarkers for treatment decisions.
  • Assessment employs single-cell transcriptomics to examine tumor microenvironments, unraveling complex cellular interactions.
  • Therapeutic strategies could be tailored based on the identified signatures, potentially improving patient outcomes.
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Cite This Study

Tang et al. (2026) studied this question.

synapsesocial.com/papers/69a76039c6e9836116a2cc02https://doi.org/10.1038/s41598-026-38219-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Bladder cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up2021 · 550 citations
  2. 2The Tumor Immune Microenvironment Drives a Prognostic Relevance That Correlates with Bladder Cancer Subtypes2019 · 238 citations
  3. 3PRELP has prognostic value and regulates cell proliferation and migration in hepatocellular carcinoma2020 · 34 citations
  4. 4Turning foes to friends: targeting cancer-associated fibroblasts2018 · 1,986 citations
  5. 5Bladder Cancer2020 · 1,833 citations