PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 3, 2026Frontiers in Pharmacology2 citationsOpen Access

A prospective feasibility study evaluating the implementation of model-informed precision dosing in critically ill children

İBİzgi BayraktarMKMerve KaşıkçıZBZuhal Benek

Key Points

  • Model-informed precision dosing may enhance treatment outcomes for critically ill children, suggesting innovative care strategies.
  • Key metrics include implementation success in clinical settings, with emphasis on potential improvements in patient care.
  • Prospective feasibility study employed comprehensive strategies for evaluating model-informed dosing in critical care environments.
  • Supports further exploration of tailored dosing approaches to optimize therapies in pediatric intensive care settings.

Abstract

ClinicalTrials.gov, identifier NCT07315438.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Bayraktar et al. (2026) studied this question.

synapsesocial.com/papers/69a76052c6e9836116a2cf45https://doi.org/10.3389/fphar.2026.1733291
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Individualized Empiric Vancomycin Dosing in Neonates Using a Model-Based Approach2017 · 57 citations
  2. 2Physiologically Based Pharmacokinetic Modeling of Antibiotics in Children: Perspectives on Model-Informed Precision Dosing2025 · 12 citations
  3. 3Prospective Evaluation of a Model-Based Dosing Regimen for Amikacin in Preterm and Term Neonates in Clinical Practice2015 · 54 citations
  4. 4TDM coupled with Bayesian forecasting should be considered an invaluable tool for optimizing vancomycin daily exposure in unstable critically ill patients2002 · 56 citations
  5. 5Clinical Utility and Safety of a Model-Based Patient-Tailored Dose of Vancomycin in Neonates2016 · 69 citations