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March 3, 2026World Journal of Orthopedics2 citationsOpen Access

Cemented vs uncemented femoral fixation in total hip arthroplasty: A systematic review and meta-analysis of periprosthetic fracture risk

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MAMohammed H. AbushalOEOsama EmbabyMMMahmoud Mersal

Key Points

  • Cemented femoral fixation is associated with a lower risk of periprosthetic fractures, although not statistically significant.
  • The analysis of limited data indicates variability in outcomes based on patient-specific factors such as age and bone quality.
  • This meta-analysis includes numerous studies to assess the relative risks of fixation types during total hip arthroplasty.
  • Further randomized controlled trials are necessary to establish clearer results regarding fixation choices and their implications.

Abstract

This meta-analysis suggests that cemented femoral fixation in primary THA may be associated with a lower risk of PFFs compared to uncemented fixation, although this finding did not reach statistical significance and was based on limited, heterogeneous data. The choice of fixation method should be individualized based on patient age, bone quality, activity level, and surgeon experience. Cemented fixation may be particularly advantageous in elderly patients and those with poor bone stock. Further high-quality randomized controlled trials with adequate follow-up are needed to provide definitive evidence.

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Cite This Study

Abushal et al. (2026) studied this question.

synapsesocial.com/papers/69a7605ac6e9836116a2d02ahttps://doi.org/10.5312/wjo.v17.i2.115615
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