Cemented vs uncemented femoral fixation in total hip arthroplasty: A systematic review and meta-analysis of periprosthetic fracture risk

This meta-analysis suggests that cemented femoral fixation in primary THA may be associated with a lower risk of PFFs compared to uncemented fixation, although this finding did not reach statistical significance and was based on limited, heterogeneous data. The choice of fixation method should be individualized based on patient age, bone quality, activity level, and surgeon experience. Cemented fixation may be particularly advantageous in elderly patients and those with poor bone stock. Further high-quality randomized controlled trials with adequate follow-up are needed to provide definitive evidence.