FRET-triggered fluorescence switching: a g-CNQDs/Cu-TCPP “turn-on” aptasensor for ultrasensitive GP73 detection

Key Points

• The aptasensor shows significant enhancement in fluorescence, achieving ultrasensitivity for GP73 detection.
• Fluorescence intensity increased by over 200% in the presence of GP73, showcasing its high sensitivity.
• Analysis using FRET principles allows for molecular recognition and specific interaction with GP73.
• This method shows promise in improving early detection strategies for liver cancer biomarkers.