Case series shows survival benefit from repeat pancreatic resection in selected patients, indicating its feasibility.
Our findings suggest that repeat pancreatic resection may be feasible in carefully selected patients with isolated local recurrence, potentially offering a survival benefit. Strict selection criteria, including the absence of distant metastases, good performance status, and technically resectable disease, appear essential to optimize outcomes, supporting the consideration of surgical re-resection as an option within a multidisciplinary management framework.
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Delis et al. (2026) studied this question.
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