Charge-dependent interfacial mechanism and conformational dynamics of lipase immobilization on ZIF-8: Insights from MD simulation and experiments

Xin Liang; Yimeng Huang; Xucheng Zhu; Prasanna J. Patil; Weiwei Li; Xiuting Li; Baoguo Sun

doi:10.1016/j.procbio.2026.02.017

February 14, 2026Process Biochemistry

Charge-dependent interfacial mechanism and conformational dynamics of lipase immobilization on ZIF-8: Insights from MD simulation and experiments

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Key Points

Lipase immobilization on ZIF-8 reveals crucial charge-dependent interfacial mechanisms.
The study demonstrates significant conformational dynamics influenced by the ZIF-8 framework.
Molecular dynamics simulations and experimental approaches validate the insights gained.
The findings may enhance strategies for enzyme immobilization in various biotechnological applications.

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Implication

Molecular dynamics simulation uncovers interfacial mechanisms of lipase immobilization on ZIF-8, indicating significant insights for enzyme applications.

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Cite This Study

Liang et al. (2026) studied this question.

synapsesocial.com/papers/69a7611ec6e9836116a2ebe5 https://doi.org/10.1016/j.procbio.2026.02.017

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Charge-dependent interfacial mechanism and conformational dynamics of lipase immobilization on ZIF-8: Insights from MD simulation and experiments

Key Points

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Implication

Discussion

Cite This Study

Charge-dependent interfacial mechanism and conformational dynamics of lipase immobilization on ZIF-8: Insights from MD simulation and experiments

Key Points

No abstract yet

Ask about this paper

Implication

Discussion

Cite This Study

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