Repurposing an ethnomedicinal herb: Horseradish (Armoracia rusticana) as a source of quorum sensing inhibitors to attenuate Pseudomonas aeruginosa virulence

Nemanja Stanisavljević; Danijel D. Milinčić; Jelena Miladinović; Jovana Ćurčić; Danka Matijašević; Milka Malešević; Milica M. Pešić; Goran N. Vukotić; Aleksandar Ž. Kostić

doi:10.1016/j.jep.2026.121378

February 14, 2026Journal of Ethnopharmacology

Repurposing an ethnomedicinal herb: Horseradish (Armoracia rusticana) as a source of quorum sensing inhibitors to attenuate Pseudomonas aeruginosa virulence

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Key Points

Quorum sensing inhibitors from horseradish effectively reduce the virulence of pseudomonas aeruginosa.
The study highlights two significant compounds derived from armoracia rusticana, showing a promising reduction in pathogenicity.
Assessment using ethnomedicine techniques demonstrates the potential of natural inhibitors in combating bacterial infections.
These findings support further research into plant-based therapies for managing biofilm-related infections.

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Implication

Observational analysis identifies quorum sensing inhibitors in horseradish, suggesting potential therapeutic applications for reducing virulence in bacteria.

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Stanisavljević et al. (2026) studied this question.

synapsesocial.com/papers/69a76159c6e9836116a2f2dd https://doi.org/10.1016/j.jep.2026.121378

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Repurposing an ethnomedicinal herb: Horseradish (Armoracia rusticana) as a source of quorum sensing inhibitors to attenuate Pseudomonas aeruginosa virulence

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Repurposing an ethnomedicinal herb: Horseradish (Armoracia rusticana) as a source of quorum sensing inhibitors to attenuate Pseudomonas aeruginosa virulence

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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