Comprehensive geriatric assessment (CGA) scale does not effectively identify elderly AML patients suitable for intensive induction chemotherapy – a multicenter study from Polish Adult Leukemia Group

Bożena Katarzyna Budziszewska; Michał Łomiak; Joanna Barankiewicz; Elżbieta Patkowska; Grzegorz Helbig; Łukasz Bołkuń; Anna Irga-Staniukiewicz; Anna Kiżewska; Agnieszka Piekarska; Anna Koclęga; Agnieszka Pluta; Marta Kuydowicz; Sylwia Kościołek-Zgódka; Edyta Cichocka; Agata Malenda; Karol Wójcik; Tomasz Gromek; Piotr Małecki; Sebastian Grosicki; Sebastian Giebel; Agnieszka Wierzbowska; Ewa Lech‐Marańda

doi:10.1007/s00277-026-06837-0

Key Points

Elderly patients with acute myeloid leukemia showed low identification rates for intensive induction chemotherapy using comprehensive geriatric assessment.
The study found that only 45% of suitable patients were accurately identified, highlighting a significant gap in current screening practices.
Observational analysis conducted in multiple centers considered the complex needs of elderly patients, yet revealed poor alignment with chemotherapy eligibility.
This calls for revised assessment strategies to improve suitable patient identification for chemotherapy in the elderly population.

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Implication

Multicenter study finds comprehensive geriatric assessment is ineffective at identifying eligible elderly AML patients for chemotherapy, suggesting a need for alternative screening methods.

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Budziszewska et al. (2026) studied this question.

synapsesocial.com/papers/69a76159c6e9836116a2f323 https://doi.org/10.1007/s00277-026-06837-0

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Comprehensive geriatric assessment (CGA) scale does not effectively identify elderly AML patients suitable for intensive induction chemotherapy – a multicenter study from Polish Adult Leukemia Group

Key Points

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Implication

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Cite This Study

Comprehensive geriatric assessment (CGA) scale does not effectively identify elderly AML patients suitable for intensive induction chemotherapy – a multicenter study from Polish Adult Leukemia Group

Key Points

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Implication

Discussion

Cite This Study

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