Stochastic dynamics at the back of a gene drive eradication wave

Léna Kläy; Léo Girardin; Florence Débarre; Vincent Calvez

doi:10.1016/j.tpb.2026.02.001

February 14, 2026Theoretical Population Biology

Stochastic dynamics at the back of a gene drive eradication wave

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Key Points

The eradication wave's dynamics reveal complex interactions among genetic manipulation techniques.
Key evidence shows that stochastic processes can drastically alter population responses in 10 scenarios tested.
Analysis of gene drive models demonstrates the significance of local population structures on overall success rates.
Support for integrating stochastic dynamics in future eradication wave strategies may enhance effectiveness.

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Implication

Observational analysis reveals population dynamics influenced by stochastic processes in genetic manipulation efforts, suggesting significant implications for eradication strategies.

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Kläy et al. (2026) studied this question.

synapsesocial.com/papers/69a76160c6e9836116a2f3f0 https://doi.org/10.1016/j.tpb.2026.02.001

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Stochastic dynamics at the back of a gene drive eradication wave

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Stochastic dynamics at the back of a gene drive eradication wave

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