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March 3, 2026CHEST Journal2 citationsOpen Access

The impact of weight loss on the physiological endotypes associated with obstructive sleep apnea

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CBCaroline BeattyAWAi-Ming WongSLShane A. Landry

Key Points

  • Improvements in apnea-hypopnea index (AHI) and airway physiology are significant with weight loss.
  • Weight loss via metabolic bariatric surgery notably enhances upper airway collapsibility and loop gain.
  • This analysis focuses on patients experiencing mild upper airway collapsibility and low loop gain to assess specific effects.
  • Such findings indicate the need for targeted interventions in managing obstructive sleep apnea associated with weight issues.

Abstract

Metabolic bariatric surgery is associated with improvements in weight, AHI, upper airway collapsibility and loop gain and may be particularly effective for those with mild upper airway collapsibility and low loop gain.

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Cite This Study

Beatty et al. (2026) studied this question.

synapsesocial.com/papers/69a761d1c6e9836116a2fe5dhttps://doi.org/10.1016/j.chest.2026.02.003
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