Recognition of Non-standard Base Pairs by Triplex-Forming Oligonucleotides Containing an Expanded Genetic Alphabet

Key Points

• Identification of non-standard base pairs enhances understanding of molecular recognition.
• Expanded genetic alphabet allows for more versatile interactions within DNA structures.
• Analysis using triplex-forming oligonucleotides reveals significant differences in binding affinities.
• These findings highlight potential applications in gene regulation and synthetic biology.