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Genetic predisposition to inflammation and psychopathology: A transdiagnostic network analysis | Synapse
March 3, 2026
Genetic predisposition to inflammation and psychopathology: A transdiagnostic network analysis
PU
Paula Usemann
Philipps University of Marburg
FD
Friederike S. David
KB
Katharina Brosch
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Key Points
Genetic predisposition influences both inflammation and psychopathology, with distinct patterns observed.
Key evidence shows specific biomarkers associated with inflammatory responses linked to mental health issues.
Network analysis highlights complex interactions between genetic factors and various psychological disorders.
This work may enable new treatment approaches, though findings require further exploration of individual variations.
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Usemann et al. (Tue,) studied this question.
synapsesocial.com/papers/69a7621dc6e9836116a30318
https://doi.org/https://doi.org/10.1016/j.jad.2026.121424