Association of Neurexin 3 (NRXN3) variants with nicotine dependence

Key Points

• Nicotine dependence is significantly associated with neurexin 3 genetic variants, indicating genetic susceptibility.
• A comprehensive examination identified several neurexin 3 variants related to tobacco usage in various populations.
• The investigation employs genetic analysis to explore the connection between neurexin 3 and nicotine dependence.
• These findings highlight the potential for genetic factors in understanding nicotine dependence, necessitating further validation.