Peucedanum praeruptorum Dunn leaves extract and its active coumarin praeroside Ⅴ alleviate ethanol-induced acute duodenal damage by suppressing apoptosis and ferroptosis in mice

Key Points

• Active coumarin praeroside V significantly reduces ethanol-induced duodenal damage in mice.
• The intervention decreases apoptosis and ferroptosis markers, supporting its protective role.
• Observational analysis involved administering Peucedanum praeruptorum extract to mice after ethanol exposure.
• These findings suggest a potential therapeutic use for Peucedanum praeruptorum in gastrointestinal injuries.