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February 1, 2026Molecular and Cellular Neuroscience

Irisin regulates mitochondrial function to support synaptogenesis in the developing hippocampus

Mary R. Josten Kyra N. Parker Crystal Dillon Heiko Jansen Gary A. Wayman

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Key Points

Irisin regulates synaptogenesis in the developing hippocampus, crucial for neuron connections.
The analysis shows that mitochondrial function is enhanced by irisin, promoting better neuronal health.
By focusing on mitochondrial function, the study explores how irisin supports brain development in young organisms.
These findings underscore the significance of irisin in neurological health, needing further exploration in broader contexts.

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Implication

Observational analysis highlights irisin's regulation of mitochondrial function in developing hippocampus, suggesting a role in neuronal development.

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Cite This Study

Josten et al. (2026) studied this question.

synapsesocial.com/papers/69a76583badf0bb9e87d95f9 https://doi.org/10.1016/j.mcn.2026.104073

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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5Single Mitochondrion Morphology‐Function Relationship Analysis Using Fluorescent Probes and Artificial Intelligence2025 · 10 citations

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