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Hypertonic solutions versus balanced crystalloids in severely burned patients: A systematic review and meta-analysis | Synapse
March 3, 2026
Open Access
Hypertonic solutions versus balanced crystalloids in severely burned patients: A systematic review and meta-analysis
RR
Romario Rivera-Sanabria
Pontificia Universidad Javeriana
MB
María-Paula Benavides
Universidad del Valle
PO
Paola-Fernanda Orbes
Universidad del Valle
Key Points
Improved outcomes were observed with hypertonic solutions in fluid resuscitation.
The review included extensive data from multiple studies, enhancing reliability.
Meta-analysis demonstrated significant benefits over standard crystalloid treatments in burn injuries.
Results indicate that different fluid management approaches may influence recovery times and complications.
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Rivera-Sanabria et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76594badf0bb9e87d99b6
https://doi.org/https://doi.org/10.1016/j.burnso.2026.100444
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