Concurrent Germline-Somatic Alterations and Associations with Cancer Outcomes: A Systematic Review of Concurrent Data Use

Key Points

• Concurrent germline and somatic alterations may significantly improve cancer outcome analysis.
• The review indicates that the integration of both data types can lead to better understanding of cancer.
• Assessment using a systematic review of existing literature highlights the potential gains.
• Improved cancer genetics applications may result from incorporating both alterations from the study design.