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February 3, 2026Current Research in Structural BiologyOpen Access

Decoding the impact of nsSNP variants on BCL6 function through integrated computational analysis

Shaden M.H. Mubarak Pardis Abdali Dehdezi Amir Razavinia Bahman KHALESI Zahra Sadat Hashemi Abolfazl Jahangiri Mohammad Reza Rahbar Mahdieh Mahboobi Saeed Khalili

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Key Points

BCL6 function is significantly affected by specific nsSNP variants, altering its activity.
Notably, certain variants led to a variation in molecular interactions and protein stability.
Integrated computational analysis of genetic variants provides insights into BCL6-related mechanisms.
This study highlights the necessity for deeper exploration into genetic variants and their functional consequences.

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Implication

Observational analysis reveals genetic impact of nsSNP variants on BCL6 function, suggesting important molecular implications.

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Cite This Study

Mubarak et al. (2026) studied this question.

synapsesocial.com/papers/69a765b9badf0bb9e87da2be https://doi.org/10.1016/j.crstbi.2026.100180

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