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Sex-Specific Differences in Outcomes and Trends in Patients With Ulcerative Colitis | Synapse
March 3, 2026
Open Access
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Sex-Specific Differences in Outcomes and Trends in Patients With Ulcerative Colitis
AR
Alissa Rothman
Johns Hopkins University
LC
Lara Chaaban
Johns Hopkins University
JM
Joanna Melia
Key Points
Patients with ulcerative colitis exhibit distinct clinical outcomes based on sex, highlighting different progression patterns.
A notable finding shows that treatment trends also vary significantly, suggesting that personalized therapies could be beneficial for optimizing care.
The analysis involved a comprehensive review of clinical data from diverse patient populations, underscoring the importance of sex as a factor.
These findings may lead to improved management strategies and further research into sex-specific biomarkers for ulcerative colitis.
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Rothman et al. (Thu,) studied this question.
synapsesocial.com/papers/69a765c6badf0bb9e87da637
https://doi.org/https://doi.org/10.1016/j.gastha.2025.100867