March 3, 2026Open Access

Cholesterol, high-density lipoprotein, glucose index as a novel marker for predicting in-stent restenosis after drug-eluting stent implantation in patients with acute coronary syndrome

Key Points

High cholesterol-glucose (CHG) index correlates with increased risk of in-stent restenosis (ISR), indicating its predictive power.
Patients experiencing acute coronary syndrome (ACS) undergoing drug-eluting stent (DES) implantation show significant associations with CHG levels.

Structured PICO

Does a high CHG index predict in-stent restenosis in ACS patients treated with DES-PCI?

Population

Patients with acute coronary syndrome (ACS) treated with drug-eluting stent percutaneous coronary intervention (DES-PCI)

Intervention

High CHG (Cholesterol, high-density lipoprotein, glucose) index

Outcome

In-stent restenosis after drug-eluting stent implantation (DES-ISR)surrogate

The CHG index may serve as a novel predictive marker for in-stent restenosis following drug-eluting stent implantation in patients with acute coronary syndrome.

Abstract

For ACS patients treated with DES-PCI, a high CHG index was found to be significantly and linearly associated with an increased risk of DES-ISR.

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