The TPx protein of Taenia solium metacestode regulates Treg and Th17 cell differentiation via the TGF-β/Smad signaling pathway | Synapse
March 3, 2026Open Access
The TPx protein of Taenia solium metacestode regulates Treg and Th17 cell differentiation via the TGF-β/Smad signaling pathway
Key Points
TPx protein from Taenia solium influences differentiation between Treg and Th17 cells.
The study highlights the importance of the TGF-β/Smad signaling pathway in this process.
Analysis reveals a significant molecular mechanism affecting immune regulation during infection.
Findings suggest potential therapeutic targets in managing immune responses related to Taenia solium.
Abstract
The TGF-β/Smad signaling pathway is a crucial molecular mechanism involved in the imbalance of Treg/Th17 cells induced by the TPx protein of T. solium metacestode.