Observational analysis highlights cerebrospinal fluid space invasion impact on progression to leptomeningeal metastasis, suggesting close monitoring is critical.
BM-CSFi, defined by preoperative MRI findings, may represent a clinically important precursor of LM. Our findings highlight the need for close monitoring of patients with BM-CSFi and the development of management protocols to minimize the risk of LM progression.
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Hong et al. (2026) studied this question.
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