Correction: Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility

Key Points

• Gq activity and β-arrestin-1 scaffolding directly influence male fertility outcomes,
• increased activity of Gq and β-arrestin-1 leads to enhanced CFTR coupling,
• Experimental assessment demonstrates the necessity of these pathways in fertility across male models,
• Findings indicate a potential therapeutic target for improving fertility; further exploration needed.