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Direct construction of sulfonated 2H-chromenes from inactivated alkynes via a photocatalytic three-component reaction | Synapse
March 3, 2026
Direct construction of sulfonated 2H-chromenes from inactivated alkynes via a photocatalytic three-component reaction
XL
Xiang Li
JZ
Jiu-Yuan Zheng
LZ
Li Zhang
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Key Points
Sulfonated 2H-chromenes are efficiently synthesized from inactivated alkynes through a novel method.
The reaction achieves notable yields, with efficiencies reaching up to 80% in optimal conditions.
Utilizing photocatalysis allows the harnessing of light energy to drive the reaction forward.
This method could expand the toolbox for organic synthesis, especially in pharmaceutical chemistry.
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Li et al. (Thu,) studied this question.
synapsesocial.com/papers/69a7676cbadf0bb9e87e0dc3
https://doi.org/https://doi.org/10.1016/j.tetlet.2026.155983
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