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March 3, 2026
Open Access
Correction: Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
WZ
Wei-Xing Zong
CL
Chi Li
Singapore National Eye Center
GH
Georgia Hatzivassiliou
Cancer Research Institute
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Key Points
Initiation of apoptosis occurs with localization of Bax and Bak to the endoplasmic reticulum, influencing cell fate.
Key finding indicates that Bax and Bak are crucial in triggering apoptosis when situated at the endoplasmic reticulum, impacting cell survival.
Observational analysis of Bax and Bak's cellular behavior highlights their roles in apoptosis through endoplasmic reticulum interaction.
This work emphasizes the significance of Bax and Bak's mechanism in apoptosis, potentially influencing therapeutic strategies against cancer.
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Zong et al. (Thu,) studied this question.
synapsesocial.com/papers/69a767f5badf0bb9e87e30f5
https://doi.org/https://doi.org/10.1083/jcb.20030208401202026c
Correction: Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis | Synapse