PPARs in Diabetic Retinopathy: Pathophysiological Insights and Emerging Pharmacological Strategies

Key Points

• Diabetic retinopathy is significantly linked to the dysfunction of PPARs, impacting vision.
• Key evidence shows that disrupted PPAR signaling pathways are associated with disease severity.
• Pathophysiological insights into PPARs inform potential pharmacological strategies for treatment.
• Understanding these mechanisms may enable new therapeutic options for diabetic retinopathy.