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March 3, 2026Current Microbiology

Synergistic Antibacterial Activity of Quercetin-Functionalized Magnetic Nanoparticles Combined with Ciprofloxacin on Pathogenic Pseudomonas Aeruginosa Via Targeting Virulence, Efflux Pump, and Adhesion-Associated Genes and Molecular Docking Analysis

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Authors

FNFarahnaz Harouni NavroudiRKReyhaneh KouchakinejadACAli Bazri Chenijani

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Overview

Observational analysis reveals enhanced antibacterial effects against Pseudomonas aeruginosa, suggesting novel treatment strategies.

Key Points

  • Quercetin-functionalized magnetic nanoparticles enhance the antibacterial activity of ciprofloxacin against Pseudomonas aeruginosa.
  • The combination notably targets virulence, efflux pump, and adhesion-associated genes, leading to effective treatment.
  • Assessment using molecular docking analysis provides insights into the interactions between nanoparticles and bacterial components.
  • Supports the development of combination therapies aimed at improving treatment outcomes against resistant bacterial infections.

Cite This Study

Navroudi et al. (2026) studied this question.

synapsesocial.com/papers/69a7688abadf0bb9e87e5091https://doi.org/10.1007/s00284-026-04718-3
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