Pre-priming cell sheet therapy enabled by dynamic wrinkled electroactive substrate for muscle reconstruction

Key Points

• Cell sheet therapy significantly improves muscle reconstruction outcomes during testing on animal models, with promising implications for tissue engineering.
• The approach utilizes a dynamic wrinkled electroactive substrate, designed to enhance regenerative capabilities within muscle tissues.
• Observational analysis demonstrated the effectiveness of this novel substrate in facilitating muscle repair processes through electrical stimulation.
• This innovative method may enable advancements in tissue engineering, offering potential applications in regenerative medicine.