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March 4, 2026Academic Radiology2 citationsOpen Access

CT Staging of Colon Cancer: Reproducibility and Pathology Association in a Multicenter Study

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JSJona ShkurtiKLKevin B. W. Groot LipmanRTRenaud L.M. Tissier

Key Points

  • The aim is to evaluate the reproducibility of CT features in staging colon cancer and their association with pathological stage.
  • Multicenter study involving multiple observers interpreting CT scans.
  • Assessment of CT features including tumor length and node diameter.
  • Evaluation of inter-observer agreement and reliability of CT staging.
  • Certain CT features are significantly linked to pathological stage.
  • Tumor length and largest node diameter show proven reproducibility.
  • Inconsistencies among different observers highlight challenges in reliable staging for treatment decisions.

Abstract

Several CT features were significantly associated with pathological stage, but their inconsistent interpretation across observers, indicates limited reliability for individualized treatment decisions. Interpretation should therefore focus on features with proven reproducibility, namely tumor length and largest node diameter, applied within standardized protocols, and integrated with the broader clinical and pathological context.

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Cite This Study

Shkurti et al. (2026) studied this question.

synapsesocial.com/papers/69a7cc4cd48f933b5eed7e8fhttps://doi.org/10.1016/j.acra.2026.02.008
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