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Commentary highlights atypical NLR pairs conferring disease resistance in wheat, suggesting complex immune mechanisms.
This commentary discusses new research showing that six structurally and functionally atypical NLR pairs in wheat confer disease resistance via a sensor NLR-helper NLR module. The functional mechanisms of some NLR pairs differ from the classical NLR pair model, revealing the complexity and diversity of the wheat immune system.
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Guan et al. (2026) studied this question.
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