Multicenter study demonstrates radiomic subtypes predict outcomes in stage I lung adenocarcinoma, suggesting tailored therapy options.
Conventional tumor-node-metastasis (TNM) staging does not adequately capture tumor heterogeneity in stage I LUAD. Three CT-based radiomic subtypes were established, with the high-risk subgroup correlating with systemic inflammatory imbalance and poorer OS. CT-based radiomic stratification identifies stage IB patients who benefit from adjuvant chemotherapy, supporting personalized postoperative management.
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Tao et al. (2026) studied this question.
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