CPB@PLH NPs accelerate wound healing by antibacterial and anti-inflammatory effects

Yilong Li; Aidi Tong; Pengxiang Xu; Li Chang; Jialong Fan; Zhoubing Shan; Qian Xie; Bin Liu

doi:10.1039/d5ra09475e

January 1, 2026RSC AdvancesOpen Access

CPB@PLH NPs accelerate wound healing by antibacterial and anti-inflammatory effects

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Key Points

The aim is to investigate the healing effects of CPB@PLH nanoparticles on diabetic wounds.
Treatment of diabetic wounds with CPB@PLH nanoparticles.
Evaluation of antibacterial activity against MRSA.
Assessment of collagen deposition, angiogenesis, and cytokine levels.
CPB@PLH NPs showed significant antibacterial activity against MRSA.
Accelerated wound healing was noted through enhanced collagen deposition.
Increased angiogenesis and modulation of cytokines were observed during treatment.

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Implication

Nanoparticles accelerate wound healing in diabetic conditions, suggesting effective therapeutic strategies.

Abstract

CPB@PLH NPs treat diabetic wounds: PLH provides antibacterial activity; CPB NPs provide ROS scavenging & anti-inflammatory effects. In MRSA -infected wounds, they accelerate healing via collagen deposition, angiogenesis, and cytokine modulation.

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Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69a7cc8ed48f933b5eed83bb https://doi.org/10.1039/d5ra09475e

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CPB@PLH NPs accelerate wound healing by antibacterial and anti-inflammatory effects

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

CPB@PLH NPs accelerate wound healing by antibacterial and anti-inflammatory effects

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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