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March 4, 2026Indian Journal of Pharmacology0 citationsOpen Access

Hexarelin Enhances Retinal Ganglion Cell Survival After Optic Nerve Transection

Hexarelin promotes the survival of retinal ganglion cells after optic nerve transection

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Authors

KCKevin Bing Shui Chow

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Overview

Demonstrates that hexarelin improves retinal ganglion cell survival after optic nerve injury, suggesting therapeutic potential.

Key Points

  • The aim is to investigate the effects of hexarelin on the survival of retinal ganglion cells after optic nerve transection.
  • Administered single and multiple doses of hexarelin
  • Monitored retinal ganglion cell survival
  • Analyzed dose-response relationship
  • Single daily doses of hexarelin increased RGC survival
  • Two daily doses further enhanced RGC survival
  • Optimal dose identified as 150 μg/kg administered twice daily
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Kevin Bing Shui Chow (2026) studied this question.

synapsesocial.com/papers/69a7cd2ad48f933b5eed9458https://doi.org/10.4103/ijp.ijp_176_24
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